A 23-year-old man is in hospital with life threatening injuries after an early morning crash on the 401 near Tilbury.
The single-vehicle crash happened in the eastbound lanes of the 401 at County Road 42 just before 7AM on Friday morning.
OPP say the vehicle left the roadway and rolled over into the highway median.
The cause of the crash remains under investigation.
The highway fully reopened to traffic just before noon.
If you have information that can assist investigators, please call Chatham Kent OPP detachment at 1-888-310-1122. Should you wish to remain anonymous, call Crime Stoppers at 1-800-222-8477 (TIPS) or submit a secure web-tip at www.cstip.ca, where you may be eligible to receive a cash reward of up to $2000.